SCHEMBL999894

SCHEMBL999894

CC(C)(C)OC(=O)NC(CC(N)=O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.49
PPARA Q07869 9/20 0.49
PPARG P37231 8/20 0.49
CTSS P25774 4/20 0.48
CTSK P43235 4/20 0.48
PPARD Q03181 2/20 0.47
ECE1 P42892 2/20 0.46
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
ACE P12821 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HTT P42858 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607848 1.00 APP (0.49) APPPPARAPPARGCTSSCTSK
SCHEMBL1486143 1.00 APP (0.49) APPPPARAPPARGCTSSCTSK
Alanine SCHEMBL5917025 0.94 APP (0.46) APPPPARAPPARGCTSSCTSK
SCHEMBL30096350 0.90 ECE1 (0.46) APPPPARAPPARGCTSSCTSK
Valine SCHEMBL5917198 0.90 ECE1 (0.46) APPPPARAPPARGCTSSCTSK
SCHEMBL7351243 0.88 CYP1A2 (0.46) APPPPARAPPARGCTSSCTSK
SCHEMBL607556 0.88 CYP1A2 (0.46) APPPPARAPPARGCTSSCTSK
SCHEMBL21638987 0.87 CTSS (0.46) PPARAPPARGCTSSCTSKPPARD
SCHEMBL21638986 0.87 CTSS (0.46) PPARAPPARGCTSSCTSKPPARD
SCHEMBL5072619 0.87 CTSS (0.44) APPPPARAPPARGCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
CN-111116417-A Cathepsin inhibitor and preparation method and application thereof 辽宁医药职业学院 2020-05-08 CN claimed
US-12625431-B2 EUV resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
EP-4043447-B1 HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVE, PREPARATION AND APPLICATION THEREOF SHANGHAI QINGDONG BIOTECHNOLOGY CO LTD (CN) 2026-01-21 EP disclosed
US-12496282-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
US-20250376461-A1 INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-12-11 US disclosed
EP-4619037-A1 SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT Lerchen, Hans-Georg (DE) 2025-09-24 EP disclosed
US-20250288573-A1 DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2025-09-18 US disclosed
EP-0574135-B1 Process for producing peptide derivatives and salts thereof JAPAN ENERGY CORP (JP) 1998-11-18 EP disclosed
US-5644028-A Process for producing peptide derivatives and salts therefor JAPAN ENERGY CORPORATION (JP) 1997-07-01 US disclosed
US-5508432-A TREATING GASTROINTESTINAL DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS GLAXO WELLCOME INC. (US) 1996-04-16 US disclosed
US-5380872-A Appetite suppresant, gall bladder disorders, CNS disorders GLAXO INC. (US) 1995-01-10 US disclosed
US-5147865-A Viricides BAYER AKTIENGESELLSCHAFT (DE) 1992-09-15 US disclosed
US-5145951-A Protected ologopeptides; treating aids BAYER AKTIENGESELLSCHAFT, A CORP. OF GERMANY (DE) 1992-09-08 US disclosed
US-5047430-A Glutamate Receptor Inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-09-10 US disclosed
EP-0437729-A2 New peptides, procedure for their preparation and their use as a medicament, especially their use as medicament against retroviruses BAYER AG (DE) 1991-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP APP 526/4885PPARA 1878/4885PPARG 853/4885
US-20250288573-A1 DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS CRBN, CD4, CDR2 APP 1846/4885PPARA 3972/4885PPARG 4028/4885
US-12625431-B2 EUV resist underlayer film-forming composition EEF1A1, ARF1, EMG1 APP 4214/4885PPARA 4500/4885PPARG 4375/4885
US-20250376461-A1 INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS TRPV3, TRPM2, TRPV1 APP 2652/4885PPARA 2981/4885PPARG 2633/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 APP 134/4885PPARA 1752/4885PPARG 2783/4885
US-12496282-B2 Hepatitis B antiviral agents HAVCR2, PYGL, SLC10A1 APP 1308/4885PPARA 1916/4885PPARG 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.