SCHEMBL29918245

SCHEMBL29918245

C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
REN P00797 1/20 0.44
BACE1 P56817 10/20 0.44
KMT2A Q03164 1/20 0.42
GLS O94925 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CYP2D6 P10635 1/20 0.40
CTSS P25774 3/20 0.40
CTSK P43235 3/20 0.40
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13755357 0.93 REN (0.46) RENBACE1KMT2AGLSCA1
SCHEMBL12555958 0.93 REN (0.46) RENBACE1KMT2AGLSCA1
SCHEMBL29283758 0.88 CYP1A2 (0.48) BACE1CA1CA2CA7CYP2D6
SCHEMBL6566148 0.88 CYP1A2 (0.48) BACE1CA1CA2CA7CYP2D6
SCHEMBL19401860 0.87 BACE1 (0.39) RENBACE1
SCHEMBL20789059 0.87 BACE1 (0.39) RENBACE1
SCHEMBL20806914 0.87 BACE1 (0.39) RENBACE1
SCHEMBL29012386 0.87 BACE1 (0.39) RENBACE1
SCHEMBL27630641 0.87 ECE1 (0.49) RENBACE1KMT2AGLSCA1
SCHEMBL27630643 0.87 ECE1 (0.49) RENBACE1KMT2AGLSCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4538279-A2 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2025-04-16 EP disclosed
US-20240209020-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2024-06-27 US disclosed
EP-3786151-B1 METHOD FOR PRODUCING AMIDE COMPOUND CHUBU UNIV EDUCATIONAL FOUNDATION (JP) 2023-06-07 EP disclosed
CN-112020492-B Method for producing amide compound 学校法人中部大学 2023-05-05 CN disclosed
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2023-01-05 US disclosed
US-11512108-B2 Method for producing amide compound CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2022-11-29 US disclosed
EP-4053132-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2022-09-07 EP disclosed
EP-4053101-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME Chubu University Educational Foundation (JP) 2022-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002422-A1 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME NAAA, NOTUM, ASNS REN 1158/4885BACE1 1531/4885KMT2A 1651/4885
US-20240209020-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME NAAA, FAAH, FAAH2 REN 1111/4885BACE1 2371/4885KMT2A 1120/4885
US-11512108-B2 Method for producing amide compound BCAT2, ASNS, VIP REN 172/4885BACE1 2814/4885KMT2A 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.