Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855200 | 0.83 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL857754 | 0.79 | KDM4E (0.41) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7976287 | 0.77 | POLB (0.42) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL855589 | 0.72 | POLB (0.49) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL855315 | 0.70 | EGFR (0.49) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2215511 | 0.70 | KDM4E (0.56) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL855661 | 0.69 | KDM4E (0.44) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7081653 | 0.67 | ACACA (0.42) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8149547 | 0.67 | ACHE (0.47) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10214298 | 0.66 | MEN1 (0.87) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809557-A | Compound | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | disclosed |