Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493878 | 0.90 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1 | |
| SCHEMBL4825828 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ERAB9A | |
| SCHEMBL15750656 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EKDM4CPTGS2RAB9A | |
| SCHEMBL4833619 | 0.79 | GAA (0.49) | ALDH1A1KDM4EPTGS1PTGS2HDAC6 | |
| SCHEMBL4833608 | 0.79 | GAA (0.49) | ALDH1A1KDM4EPTGS1PTGS2HDAC6 | |
| SCHEMBL4831278 | 0.78 | KMT2A (0.43) | ALDH1A1KDM4EPTGS1PTGS2HDAC6 | |
| SCHEMBL27032558 | 0.77 | MITF (0.49) | ALDH1A1KDM4EPKMMITFHTT | |
| SCHEMBL15750441 | 0.76 | LMNA (0.58) | ALDH1A1KDM4ERAB9ANPSR1L3MBTL1 | |
| SCHEMBL21333090 | 0.76 | MITF (0.48) | KDM4EPKMMITFHTTRAB9A | |
| SCHEMBL21409623 | 0.75 | CYP19A1 (0.47) | ALDH1A1HDAC6HDAC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1731994-A | Prophylactic and therapeutic agent for neuropathy | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-08 | — | — | CN | disclosed |