Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613169 | 0.82 | CCNC (0.46) | BPTFBRD4PRMT5WDR77RAB9A | |
| SCHEMBL4829311 | 0.81 | RAB9A (0.43) | PRMT5WDR77RAB9ASMN1; SMN2DUSP3 | |
| SCHEMBL4829107 | 0.80 | PRMT5 (0.40) | PRMT5WDR77RAB9ASMN1; SMN2HIF1A | |
| SCHEMBL4836369 | 0.80 | PTGS2 (0.42) | RAB9ASMN1; SMN2HIF1ANPC1LMNA | |
| SCHEMBL3630473 | 0.80 | NR3C2 (0.41) | BPTFPRMT5WDR77HIF1ALMNA | |
| SCHEMBL4836837 | 0.79 | LMNA (0.46) | PRMT5WDR77RAB9ASMN1; SMN2HIF1A | |
| SCHEMBL4831072 | 0.77 | MEN1 (0.44) | PRMT5WDR77CYP2A6LMNAMAPT | |
| SCHEMBL28806382 | 0.76 | HRH3 (0.42) | BPTFBRD4PRMT5WDR77HRH3 | |
| SCHEMBL4831559 | 0.76 | PDE2A (0.42) | LMNA | |
| SCHEMBL27945783 | 0.74 | PRMT5 (0.35) | BPTFBRD4PRMT5WDR77HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1731994-A | Prophylactic and therapeutic agent for neuropathy | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-08 | — | — | CN | disclosed |