Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288088 | 0.80 | KIF11 (0.47) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL27466975 | 0.79 | KIF11 (0.46) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL30662035 | 0.79 | BCL2L1 (0.48) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL27528878 | 0.79 | BCL2L1 (0.48) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL27772008 | 0.79 | HPRT1 (0.47) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL27430162 | 0.79 | KIF11 (0.46) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL28118478 | 0.77 | KIF11 (0.45) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL30928215 | 0.74 | HPRT1 (0.54) | KIF11TSHRNQO1 | |
| SCHEMBL21176632 | 0.74 | HPRT1 (0.54) | KIF11TSHRNQO1 | |
| SCHEMBL2089665 | 0.74 | HPRT1 (0.54) | KIF11TSHRNQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164849-B | Heterogeneous hydrogen-catalyst reactor | 辉光能源公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-101851190-B | Biscarbazol-9-yl-substituted triarylamine | SUMITOMO CHEMICAL CO | 2012-04-25 | — | — | CN | disclosed |
| CN-101851190-A | The triarylamine of two carbazoles-9-base-replacement | SUMITOMO CHEMICAL CO | 2010-10-06 | — | — | CN | disclosed |
| CN-100536850-C | Combinations comprising staurosporines | NOVARTIS AG (CH) | 2009-09-09 | — | — | CN | disclosed |
| CN-101495534-A | Dicarbazole aromatic amine polymers and electronic devices | SUMITOMO CHEMICAL CO (JP) | 2009-07-29 | — | — | CN | disclosed |
| CN-100457111-C | Use of staurosporine derivatives for the preparation of a medicament | NOVARTIS AG (CH) | 2009-02-04 | — | — | CN | disclosed |
| CN-101304749-A | Compositions and methods for less immunogenic pr0tein-lip1d complexes | RES FOUNDATION OF STATE OF UNI (CH) | 2008-11-12 | — | — | CN | disclosed |
| CN-101164539-A | New use of staurosporine derivatives | NOVARTIS AG (CH) | 2008-04-23 | — | — | CN | disclosed |
| CN-101133098-A | Polymers and electronic devices containing dicarbazol-9-yl-substituted triarylamines | SUMITOMO CHEMICAL CO (JP) | 2008-02-27 | — | — | CN | disclosed |
| CN-1832747-A | Combinations comprising staurosporines | NOVARTIS AG (CH) | 2006-09-13 | — | — | CN | disclosed |
| CN-1816333-A | Staurosporine derivatives for hypereosinophilic syndrome | NOVARTIS AG (CH) | 2006-08-09 | — | — | CN | disclosed |
| CN-1805749-A | New pharmaceutical use of staurosporine derivatives | NOVARTIS AG (CH) | 2006-07-19 | — | — | CN | disclosed |