Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | NQO1 | P15559 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthol SCHEMBL27426941 | 0.86 | HPRT1 (0.46) | HPRT1KIF11L3MBTL1BCL2L1BAD | |
| Betanaphthol SCHEMBL27451711 | 0.85 | HPRT1 (0.45) | HPRT1KIF11BCL2L1BADNQO1 | |
| Quinoline SCHEMBL28793169 | 0.84 | ALDH1A1 (0.42) | HPRT1KIF11TSHRHTR3EHTR3B | |
| Isoquinoline SCHEMBL27659509 | 0.84 | HPRT1 (0.41) | HPRT1KIF11NQO1 | |
| SCHEMBL27721426 | 0.84 | KIF11 (0.44) | KIF11TSHRL3MBTL1BCL2L1BAD | |
| SCHEMBL27288088 | 0.80 | KIF11 (0.47) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL27528878 | 0.79 | BCL2L1 (0.48) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL30662035 | 0.79 | BCL2L1 (0.48) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL27466975 | 0.79 | KIF11 (0.46) | KIF11TSHRBCL2L1BADCDK4 | |
| SCHEMBL27430162 | 0.79 | KIF11 (0.46) | KIF11TSHRBCL2L1BADCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500996-A | (3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-08-05 | — | — | CN | disclosed |