SCHEMBL27632207

SCHEMBL27632207

CCCc1cc(Br)c(O)c(C(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.47
GABRB1 P18505 4/20 0.47
GSR P00390 1/20 0.44
GABRB2 P47870 3/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
GABRA2 P47869 1/20 0.44
GABRA4 P48169 1/20 0.44
GABRA6 Q16445 1/20 0.44
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
THRA P10827 4/20 0.37
THRB P10828 4/20 0.37
MAPT P10636 1/20 0.37
TRPA1 O75762 1/20 0.37
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
HSP90AB1 P08238 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603030 0.87 GABRA1 (0.53) GABRA1GABRB1GSRGABRB2GABRA5
SCHEMBL13057520 0.87 GSR (0.57) GABRA1GABRB1GSRGABRB2GABRA5
SCHEMBL542182 0.82 CYP3A4 (0.46) CA1CA2THRATHRBCNR1
SCHEMBL4788370 0.79 GABRA1 (0.47) GABRA1GABRB1GSRGABRB2GABRA5
Bicarbonate SCHEMBL11439022 0.76 PTPN1 (0.47) THRATHRBCNR1CNR2
SCHEMBL27613126 0.76 PTGS2 (0.43) CA1CA2CNR1CNR2
SCHEMBL200138 0.76 GABRA1 (0.60) GABRA1GABRB1GSRGABRB2GABRA5
SCHEMBL13323514 0.74 CNR1 (0.37) CA1CA2THRATHRBCNR1
SCHEMBL5401475 0.74 CYP2D6 (0.40) THRATHRBCNR1CNR2
SCHEMBL5182611 0.74 CNR1 (0.37) THRATHRBMAPTCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100500734-C Method for making copolycarbonates GEN ELECTRIC (NL) 2009-06-17 CN claimed
CN-1732203-A Method for making copolycarbonates GEN ELECTRIC (US) 2006-02-08 CN claimed
CN-112313277-B Polyethylene with polycarbonate-siloxane for improved environmental stress cracking resistance SABIC环球技术有限责任公司 2023-06-13 CN disclosed
CN-113166500-A Polyethylene with additives for increasing environmental stress crack resistance SABIC环球技术有限责任公司 2021-07-23 CN disclosed
CN-108463481-B Method for producing polycarbonate 国际壳牌研究有限公司 2021-04-09 CN disclosed
CN-112313277-A Polyethylene with polycarbonate-siloxane for improved environmental stress crack resistance SABIC环球技术有限责任公司 2021-02-02 CN disclosed
CN-108473672-B Process for preparing melt polycarbonate 国际壳牌研究有限公司 2020-12-08 CN disclosed
CN-101336231-B Methods for increasing the mean particle size of 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidines SABIC INNOVATIVE PLASTICS IP 2013-04-17 CN disclosed
CN-101796109-B Polymer foam having nanocellular morphology and method of making same SABIC INNOVATIVE PLASTICS IP 2012-12-26 CN disclosed
CN-102775752-A Polymeric foams with nanocellular morphology and methods for making them SABIC INNOVATIVE PLASTICS IP 2012-11-14 CN disclosed
CN-102516518-A Method of preparing polycarbonate SABIC INNOVATIVE PLASTICS IP 2012-06-27 CN disclosed
CN-101336231-A Methods for increasing the mean particle size of 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidines GEN ELECTRIC (US) 2008-12-31 CN disclosed
CN-101331169-A Equipment cleaning in polycarbonate manufacture GEN ELECTRIC (US) 2008-12-24 CN disclosed
CN-101080380-A Process for the preparation of aliphatic chloroformates GEN ELECTRIC (US) 2007-11-28 CN disclosed
CN-101056913-A Process to make polycarbonate from bismethylsalicylcarbonate (BMSC) GEN ELECTRIC (US) 2007-10-17 CN disclosed
CN-101050275-A Method and apparatus to make high molecular weight melt polycarbonate GEN ELECTRIC (US) 2007-10-10 CN disclosed
CN-1972982-A Method for preparing a polycarbonate oligomer mixture at low temperature for manufacturing polycarbonate GEN ELECTRIC (US) 2007-05-30 CN disclosed
CN-1914248-A Process for the production of copolycarbonates with reduced color GEN ELECTRIC (US) 2007-02-14 CN disclosed
CN-1732203-A Method for making copolycarbonates GEN ELECTRIC (US) 2006-02-08 CN disclosed
CN-1694914-A Method and apparatus for preparing high molecular weight melt polycarbonate GEN ELECTRIC (US) 2005-11-09 CN disclosed