Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27334604 | 0.90 | TDP1 (0.44) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL27665453 | 0.77 | TUBB1 (0.35) | KDM4EHTTLMNA | |
| SCHEMBL29396391 | 0.77 | TDP1 (0.62) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL1179747 | 0.77 | TDP1 (0.62) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL14553753 | 0.77 | TDP1 (0.50) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL16738853 | 0.75 | TDP1 (0.49) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL30673293 | 0.75 | TDP1 (0.49) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL27759581 | 0.74 | TUBB1 (0.33) | POLBHTTLMNA | |
| SCHEMBL7033341 | 0.74 | ALDH1A1 (0.42) | TDP1L3MBTL1ALDH1A1CYP19A1MAPT | |
| SCHEMBL11016571 | 0.73 | RAB9A (0.34) | KDM4EPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1798730-A | Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2006-07-05 | — | — | CN | disclosed |
| CN-1768054-A | Novel cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors | AVENTIS PHARMA SA (FR) | 2006-05-03 | — | — | CN | disclosed |