Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064672 | 0.84 | TAAR1 (0.47) | LMNAHTTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL6864047 | 0.78 | ALDH1A1 (0.41) | LMNAHTTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL850463 | 0.76 | LMNA (0.54) | LMNAHTTKMT2AALDH1A1MAPT | |
| SCHEMBL3682694 | 0.76 | HTT (0.55) | HTTKMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL27670903 | 0.75 | KIF11 (0.46) | LMNAKMT2AALDH1A1THRBMAPT | |
| SCHEMBL1636346 | 0.74 | ALDH1A1 (0.51) | LMNAKMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL879705 | 0.73 | SMN1; SMN2 (0.47) | LMNAKMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL3868208 | 0.73 | MEN1 (0.57) | LMNAHTTKMT2AALDH1A1HPGD | |
| SCHEMBL20150737 | 0.73 | MAPT (0.67) | LMNAHTTKMT2AALDH1A1MAPT | |
| SCHEMBL4820385 | 0.71 | HSD17B10 (0.61) | KMT2AALDH1A1HPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1692115-A | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-11-02 | — | — | CN | disclosed |