Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 5/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157574 | 0.86 | GAA (0.48) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL5157783 | 0.86 | ACACB (0.43) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL5159586 | 0.85 | SMPD1 (0.54) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL2763285 | 0.83 | ACACB (0.44) | ACACBGPR139ATMALDH1A1NPC1 | |
| SCHEMBL20810461 | 0.82 | ACACB (0.42) | GAAKMT2AACACBALDH1A1NPC1 | |
| SCHEMBL5155226 | 0.75 | GAA (0.45) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL5157915 | 0.74 | GAA (0.44) | GAAKMT2AHSD17B10SMPD1ATM | |
| SCHEMBL9717443 | 0.74 | GAA (0.77) | GAAKMT2AHSD17B10SMPD1ATM | |
| SCHEMBL20810494 | 0.73 | SMN1; SMN2 (0.52) | GAAACACBSMN1; SMN2MAPT | |
| SCHEMBL16799628 | 0.73 | HDAC8 (0.45) | ACACBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177503-A1 | MODULATORS OF CANNABINOID RECEPTORS | UCL Business PLC (GB) | 2010-04-21 | — | — | EP | disclosed |
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |