Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157574 | 0.89 | GAA (0.48) | SMPD1GAAKMT2AHSD17B10ACACB | |
| SCHEMBL20810362 | 0.85 | SMN1; SMN2 (0.50) | SMPD1GAAACACBSMN1; SMN2MMP2 | |
| SCHEMBL2763286 | 0.85 | GAA (0.44) | SMPD1GAAKMT2AHSD17B10ACACB | |
| SCHEMBL5157783 | 0.84 | ACACB (0.43) | SMPD1GAAKMT2AHSD17B10ACACB | |
| SCHEMBL20810494 | 0.83 | SMN1; SMN2 (0.52) | GAAACACBSMN1; SMN2MAPT | |
| SCHEMBL2763802 | 0.81 | ACACB (0.49) | ACACBSMN1; SMN2MMP2MMP12ATM | |
| SCHEMBL20810296 | 0.78 | MAPK1 (0.49) | GAAKMT2AACACBSMN1; SMN2MAPT | |
| SCHEMBL5155226 | 0.77 | GAA (0.45) | SMPD1GAAKMT2AHSD17B10ACACB | |
| SCHEMBL9717443 | 0.76 | GAA (0.77) | SMPD1GAAKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL5155596 | 0.76 | SMPD1 (0.55) | SMPD1GAAKMT2AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |