Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 5/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159586 | 0.89 | SMPD1 (0.54) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL2763286 | 0.86 | GAA (0.44) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL5157783 | 0.85 | ACACB (0.43) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL2763155 | 0.82 | ACACB (0.48) | ACACBATMALDH1A1 | |
| SCHEMBL17049470 | 0.81 | ACACB (0.58) | GAAKMT2AACACBATMALDH1A1 | |
| SCHEMBL5155226 | 0.78 | GAA (0.45) | GAAKMT2AHSD17B10ACACBSMPD1 | |
| SCHEMBL9717443 | 0.77 | GAA (0.77) | GAAKMT2AHSD17B10SMPD1ATM | |
| SCHEMBL31753430 | 0.77 | CYP4A11 (0.55) | ALDH1A1 | |
| SCHEMBL16799629 | 0.77 | CYP4A11 (0.55) | ALDH1A1 | |
| SCHEMBL20810494 | 0.76 | SMN1; SMN2 (0.52) | GAAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745011-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL Biomedica plc (GB) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005080316-A2 | MODULATORS OF CANNABINOID RECEPTORS | UCL BIOMEDICA PLC. (GB) | 2005-09-01 | — | — | WO | disclosed |