SCHEMBL27633009

SCHEMBL27633009

O=C1C=Cc2cc(Cl)ccc21.[H+].[H+]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 3/20 0.46
PTPN11 Q06124 1/20 0.43
PPOX P50336 1/20 0.42
CDC25A P30304 4/20 0.41
CDC25C P30307 4/20 0.41
CES1 P23141 1/20 0.38
IDO1 P14902 2/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CDC25B P30305 1/20 0.37
AKT1 P31749 1/20 0.37
SNCA P37840 1/20 0.37
MAP2K1 Q02750 1/20 0.37
PIN1 Q13526 1/20 0.37
EHMT2 Q96KQ7 1/20 0.37
NSD1 Q96L73 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
METAP1 P53582 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PTPRC P08575 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646750 0.98 S100A4 (0.48) S100A4PTPN11PPOXCDC25ACDC25C
SCHEMBL2527823 0.85 PTPRC (0.52) S100A4PTPN11PPOXCDC25ACDC25C
SCHEMBL14244621 0.80 PTPN11 (0.48) S100A4PTPN11PPOXCDC25ACDC25C
SCHEMBL8773134 0.79 S100A4 (0.58) S100A4PTPN11PPOXCDC25ACDC25C
SCHEMBL11858854 0.76 S100A4 (0.50) S100A4CDC25ACDC25CCES1IDO1
SCHEMBL29043530 0.71 ALDH1A1 (0.43) S100A4CES1IDO1MAOAMAOB
SCHEMBL2896364 0.71 CA1 (0.45) S100A4CDC25ACDC25CCES1IDO1
SCHEMBL8221556 0.71 PTPRC (0.59) S100A4CDC25ACDC25CIDO1MAOA
SCHEMBL30598693 0.71 PTPRC (0.59) S100A4CDC25ACDC25CIDO1MAOA
SCHEMBL1500055 0.71 S100A4 (0.48) S100A4CES1IDO1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100396706-C Polyolefin block copolymers EQUISTAR CHEM LP (US) 2008-06-25 CN disclosed
CN-1671756-A Polyolefin block copolymers EQUISTAR CHEM LP (US) 2005-09-21 CN disclosed