Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.58 |
| ▸ | PPOX | P50336 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 4/20 | 0.45 |
| ▸ | CDC25C | P30307 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646750 | 0.81 | S100A4 (0.48) | S100A4PPOXPTPN11HSP90AA1CDC25B | |
| SCHEMBL14244621 | 0.81 | PTPN11 (0.48) | S100A4PPOXPTPN11HSP90AA1CDC25B | |
| SCHEMBL27633009 | 0.79 | S100A4 (0.46) | S100A4PPOXPTPN11HSP90AA1CDC25B | |
| SCHEMBL29581505 | 0.74 | S100A4 (0.71) | S100A4PPOXPTPN11HSP90AA1CDC25B | |
| SCHEMBL353693 | 0.74 | S100A4 (0.80) | S100A4PPOXHSP90AA1CDC25BIDO1 | |
| SCHEMBL1133148 | 0.74 | S100A4 (0.90) | S100A4PPOXHSP90AA1MAOAMAOB | |
| SCHEMBL4229683 | 0.74 | S100A4 (0.80) | S100A4PPOXHSP90AA1CDC25BIDO1 | |
| SCHEMBL4319897 | 0.74 | S100A4 (0.71) | S100A4PPOXPTPN11HSP90AA1CDC25B | |
| SCHEMBL30345128 | 0.74 | S100A4 (0.90) | S100A4PPOXHSP90AA1MAOAMAOB | |
| SCHEMBL2599342 | 0.74 | S100A4 (1.00) | S100A4PPOXHSP90AA1CES1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756717-A | Tolvaptan intermediate and preparation method of tollvaptan | 广州市桐晖药业有限公司 | 2024-03-26 | — | — | CN | claimed |
| US-4460674-A | GALLIC ACID DERIVATIVES AND NAPOHTHOQUINONES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | claimed |
| US-20240380007-A1 | ANTHRAQUINONE COMPOUND-CONTAINING NON-AQUEOUS ELECTROLYTE SOLUTION AND SECONDARY BATTERY INCLUDING THE SAME | AIR WATER PERFORMANCE CHEMICAL INC. (JP) | 2024-11-14 | — | — | US | disclosed |
| CN-117756717-A | Tolvaptan intermediate and preparation method of tollvaptan | 广州市桐晖药业有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117581407-A | Nonaqueous electrolyte containing anthraquinone compound and secondary battery comprising same | 爱沃特高能化工株式会社 | 2024-02-20 | — | — | CN | disclosed |
| US-11767308-B2 | Method of stabilizing perfluorodioxolane compound, perfluorodioxolane compound-containing composition and method of producing perfluorodioxolane compound polymer | TOSOH CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11767308-B2 | Method of stabilizing perfluorodioxolane compound, perfluorodioxolane compound-containing composition and method of producing perfluorodioxolane compound polymer | TOSOH CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2023-03-28 | — | — | US | disclosed |
| WO-2023032362-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION CONTAINING ANTHRAQUINONE COMPOUND AND SECONDARY BATTERY INCLUDING SAME | エア・ウォーター・パフォーマンスケミカル株式会社 | 2023-03-09 | — | — | WO | disclosed |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2021-04-29 | — | — | US | disclosed |
| EP-0439585-B1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | MAG GEORG MAYRHOFER & CO OHG (AT) | 1997-10-29 | — | — | EP | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4593120-A | Naphthalene-1,4-dicarboxylic acid group | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0107512-B1 | 1,4-ACYLOXYNAPHTHALENE DERIVATIVES, TOPICAL COMPOSITIONS CONTAINING THEM, METHODS FOR THEIR PREPARATION, AND INTERMEDIATES THEREFOR | SYNTEX (U.S.A.) INC. (US) | 1986-02-26 | — | — | EP | disclosed |
| EP-0146145-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-06-26 | — | — | EP | disclosed |
| US-4466981-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4460674-A | GALLIC ACID DERIVATIVES AND NAPOHTHOQUINONES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| EP-0107512-A1 | 1,4-Acyloxynaphthalene derivatives, topical compositions containing them, methods for their preparation, and intermediates therefor | SYNTEX (U.S.A.) INC. (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4442127-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1984-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767308-B2 | Method of stabilizing perfluorodioxolane compound, perfluorodioxolane compound-containing composition and method of producing perfluorodioxolane compound polymer | PFAS, PFN1, PFKFB1 | S100A4 3598/4885PPOX 159/4885PTPN11 823/4885 |
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | PPOX, NOX4, CROCC | S100A4 1775/4885PPOX 1/4885PTPN11 3015/4885 |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | PPOX, NOX4, CROCC | S100A4 1775/4885PPOX 1/4885PTPN11 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.