SCHEMBL561406

SCHEMBL561406

O=C(O)C=CC(O)CCCCCCCCCCCCCCO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.49
BACE1 P56817 1/20 0.49
GPR84 Q9NQS5 1/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
PTPN1 P18031 1/20 0.38
PPARG P37231 2/20 0.37
GPR132 Q9UNW8 1/20 0.37
TRPA1 O75762 1/20 0.36
DDAH1 O94760 1/20 0.36
GAPDH P04406 1/20 0.36
MAPT P10636 1/20 0.36
FAAH O00519 1/20 0.35
CAMK2A Q9UQM7 1/20 0.34
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4745520 1.00 ACHE (0.49) ACHEBACE1GPR84FFAR1FFAR4
SCHEMBL27963352 1.00 ACHE (0.49) ACHEBACE1GPR84FFAR1FFAR4
SCHEMBL15287182 1.00 ACHE (0.49) ACHEBACE1GPR84FFAR1FFAR4
SCHEMBL649787 1.00 ACHE (0.49) ACHEBACE1GPR84FFAR1FFAR4
SCHEMBL15286996 1.00 ACHE (0.49) ACHEBACE1GPR84FFAR1FFAR4
SCHEMBL4759937 1.00 ACHE (0.49) ACHEBACE1GPR84FFAR1FFAR4
Adipic Acid SCHEMBL6760249 0.93 FFAR1 (0.55) ACHEBACE1GPR84FFAR1FFAR4
SCHEMBL2763308 0.92 ACHE (0.52) ACHEBACE1GPR84FFAR1FFAR4
SCHEMBL23647621 0.87 ACHE (0.67) ACHEBACE1PPARGGPR132TRPA1
SCHEMBL21049245 0.87 ACHE (0.67) ACHEBACE1PPARGGPR132TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768873-A Viable cell constructs for biosynthesizing dairy products, and products and methods related thereto 谢恩·吉利亚诺 2023-03-07 CN claimed
US-20230059978-A1 LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS GUILIANO SHAYNE (US) 2023-02-23 US claimed
EP-4087915-A1 LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS Guiliano, Shayne (US) 2022-11-16 EP claimed
WO-2021142241-A1 LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS GUILIANO SHAYNE (US) 2021-07-15 WO claimed
EP-3515498-B1 INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN FRAUNHOFER GES FORSCHUNG (DE) 2021-03-03 EP claimed
EP-3515498-A1 INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V. (DE) 2019-07-31 EP claimed
US-20190211397-A1 INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2019-07-11 US claimed
CN-109715212-A For preventing and/or treating the GPR132 inhibitor of neuropathic pain caused by chemotherapy 弗劳恩霍夫应用研究促进协会 2019-05-03 CN claimed
WO-2018055082-A1 INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-03-29 WO claimed
EP-3299032-A1 INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-03-28 EP claimed
CN-104245800-B Novel benzene polycarboxylic acid compound RD创新有限公司 2017-09-08 CN claimed
US-9644074-B2 Benzene polycarboxylic acid compounds and their use as drug RINNOVATION APS (DK) 2017-05-09 US claimed
EP-2831151-B1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDINNOVATION APS (DK) 2016-12-14 EP claimed
US-20160017104-A1 Benzene Polycarboxylic Acid Compounds and Their Use as Drug RDINNOVATION APS (DK) 2016-01-21 US claimed
EP-2831151-A1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDInnovation ApS (DK) 2015-02-04 EP claimed
WO-2013143549-A1 BENZENE POLYCARBOXYLIC ACID COMPOUNDS AND THEIR USE AS DRUG RDINNOVATION APS (DK) 2013-10-03 WO claimed
CN-118542862-A Application of pinocembrin in preparation of aromatic hydrocarbon receptor regulator 中国科学院华南植物园 2024-08-27 CN disclosed
US-20230400469-A1 RAPID INTRA-CELLULAR ASSAY ESSENLIX CORPORATION (US) 2023-12-14 US disclosed
US-6525006-B2 Can be used to metal processing such as cutting, grinding and plastic working KYODO YUSHI CO., LTD. (JP) 2003-02-25 US disclosed
US-20020193263-A1 Lubricant composition KYODO YUSHI CO., LTD. (JP) 2002-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160017104-A1 Benzene Polycarboxylic Acid Compounds and Their Use as Drug PAH, HPD, PLOD2 ACHE 1248/4885BACE1 1750/4885GPR84 2203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.