SCHEMBL27633124

SCHEMBL27633124

CCc1ccc(CCc2cc(C(=O)O)cc(C(=O)O)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
RXRA P19793 2/20 0.49
RXRB P28702 2/20 0.49
RARB P10826 6/20 0.47
CA12 O43570 1/20 0.45
ALPL P05186 1/20 0.45
CA9 Q16790 1/20 0.45
BCL2 P10415 1/20 0.45
MEN1 O00255 1/20 0.45
RARA P10276 1/20 0.45
MAPT P10636 1/20 0.45
MTOR P42345 1/20 0.45
KMT2A Q03164 1/20 0.45
PLK1 P53350 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 1/20 0.42
GPR84 Q9NQS5 1/20 0.42
CTRC Q99895 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1353367 0.83 ALDH1A1 (0.60) ALDH1A1RXRARXRBCA12CA9
SCHEMBL16749638 0.83 CA12 (0.48) ALDH1A1CA12CA9MEN1MAPT
SCHEMBL27766830 0.82 GAA (0.59) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL12243316 0.81 ALDH1A1 (0.77) ALDH1A1RXRARXRBRARBBCL2
SCHEMBL28069551 0.81 PTGS1 (0.50) ALDH1A1NPC1RAB9A
SCHEMBL28089634 0.81 RXRA (0.49) RXRARXRBMEN1KMT2AGAA
SCHEMBL27646690 0.80 CA1 (0.58) NPC1RAB9ASMN1; SMN2
SCHEMBL1355567 0.79 ALDH1A1 (0.45) ALDH1A1RXRARXRBRARBCA12
SCHEMBL19901 0.79 ALDH1A1 (1.00) ALDH1A1RXRARXRBRARBBCL2
SCHEMBL1330335 0.79 ALDH1A1 (1.00) ALDH1A1RXRARXRBRARBBCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1761676-A Heteroaryl 5-thio-beta-d-glucopyranoside derivatives and remedies for diabetes containing the same TAISHO PHARMACEUTICAL CO LTD (JP) 2006-04-19 CN disclosed