Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751256 | 0.85 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1299991 | 0.79 | HCAR2 (0.42) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4875428 | 0.79 | MGAM (0.50) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13730417 | 0.79 | — | — | |
| SCHEMBL13296266 | 0.79 | MGAM (0.50) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3390814 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL1260928 | 0.77 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1260927 | 0.77 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9654807 | 0.76 | — | — | |
| SCHEMBL9912439 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957233-B2 | Method for producing optically active 1,2-bis(dialkylphosphino)benzene derivative | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2015-02-17 | — | — | US | disclosed |
| US-20130172597-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 1,2-BIS(DIALKYLPHOSPHINO)BENZENE DERIVATIVE | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2013-07-04 | — | — | US | disclosed |
| US-7858348-B2 | N-acetyl-(R,S)-beta-amino acid acylase gene | AJINOMOTO CO., INC. (JP) | 2010-12-28 | — | — | US | disclosed |
| EP-1882740-B1 | N-acetyl-(R,S)-B-amino acid acylase gene | AJINOMOTO KK (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-20080241895-A1 | N-Acetyl-(R,S)-beta-Amino Acid Acylase Gene | AJINOMOTO CO., INC. (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1882740-A1 | N-acetyl-(R,S)-B-amino acid acylase gene | Ajinomoto Co., Ltd. (JP) | 2008-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172597-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 1,2-BIS(DIALKYLPHOSPHINO)BENZENE DERIVATIVE | RDX, BRIX1, P2RX1 | HCAR2 1364/4885KEAP1 1917/4885NFE2L2 3567/4885 |
| US-20080241895-A1 | N-Acetyl-(R,S)-beta-Amino Acid Acylase Gene | ACSL4, FASN, BLVRB | HCAR2 4339/4885KEAP1 3317/4885NFE2L2 3800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.