Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3496060 | 0.77 | NOTUM (0.64) | ALDH1A1ADRA1DL3MBTL1KDM4ELMNA | |
| SCHEMBL5762448 | 0.75 | THRB (0.51) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4273292 | 0.71 | NOTUM (0.52) | KDM4EKMT2ANOTUM | |
| SCHEMBL20893846 | 0.71 | TSHR (0.51) | DHPSALDH1A1ADRA1DKDM4ENAPRT | |
| SCHEMBL12120857 | 0.70 | HDAC3 (0.57) | DHPSKDM4ELMNAHTTNAPRT | |
| SCHEMBL3495559 | 0.69 | CYP19A1 (0.55) | ALDH1A1KDM4ELMNANOTUMTSHR | |
| SCHEMBL16220643 | 0.68 | CHRNB2 (0.51) | DHPSL3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL27638474 | 0.68 | ADRA1D (0.43) | DHPSALDH1A1ADRA1DL3MBTL1KDM4E | |
| SCHEMBL7809472 | 0.67 | KMT2A (0.60) | KDM4EKMT2AHDAC1HDAC2HDAC10 | |
| SCHEMBL6840334 | 0.67 | PLAU (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100427472-C | Aryl-heteroaromatic compounds, compositions containing them and their use | AVENTIS PHARMA SA (FR) | 2008-10-22 | — | — | CN | disclosed |
| CN-1829697-A | Aryl-heteroaromatic products, compositions containing same and use thereof | AVENTIS PHARMA SA (FR) | 2006-09-06 | — | — | CN | disclosed |