Glutarate

Glutarate

SCHEMBL27633876

C(OCC1CO1)C1CO1.O=C(O)CCCC(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
SLC22A6 Q4U2R8 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 5/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPK1 P28482 1/20 0.41
LMNA P02545 3/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
MGLL Q99685 2/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL475382 0.96 TSHR (0.50) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Azelaic Acid SCHEMBL27634510 0.94 TSHR (0.48) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Sebacic Acid SCHEMBL11139033 0.94 TSHR (0.48) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Octanedioate SCHEMBL27634532 0.94 TSHR (0.48) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Succinic Acid SCHEMBL27818706 0.91 TSHR (0.48) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Valeric Acid SCHEMBL27871802 0.89 SMN1; SMN2 (0.56) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Stearic Acid SCHEMBL7600941 0.86 ALDH1A1 (0.59) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Decanoic Acid SCHEMBL27807530 0.86 ALDH1A1 (0.59) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Octanoic Acid SCHEMBL9233254 0.86 ALDH1A1 (0.59) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1
Palmitic Acid SCHEMBL28990447 0.86 ALDH1A1 (0.59) TSHRSLC22A6SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1732883-A Cationically curable composition for dental use TOKUYAMA CORP (JP) 2006-02-15 CN disclosed