Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403275 | 0.74 | MAPT (0.79) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL4304080 | 0.73 | SMN1; SMN2 (0.57) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL4312684 | 0.73 | MGAM (0.56) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL237343 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL28869279 | 0.71 | MAPT (0.55) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL3954441 | 0.70 | MGAM (0.66) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL6955948 | 0.69 | MGAM (0.63) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL5176927 | 0.69 | MGAM (0.63) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL10635595 | 0.68 | MGAM (0.58) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL5974972 | 0.68 | MGAM (0.62) | KMT2AL3MBTL1MEN1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1849328-A | Novel 14 and 15 membered-ring compounds | GLAXO GROUP LTD (GB) | 2006-10-18 | — | — | CN | disclosed |
| CN-1820017-A | Macrolides substituted at the 4 \"position | GLAXO GROUP LTD (GB) | 2006-08-16 | — | — | CN | disclosed |