SCHEMBL2763485

SCHEMBL2763485

CC(C)[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.35
HTR2A P28223 2/20 0.33
HTR6 P50406 1/20 0.33
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8733906 0.87 SLC22A2 (0.31) SIGMAR1MEN1KMT2A
SCHEMBL3380394 0.81 HTR2A (0.35) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL6919016 0.81 HTR6 (0.31) SIGMAR1HTR2AHTR6
SCHEMBL441993 0.80 SIGMAR1 (0.32) SIGMAR1HTR2AHTR6
SCHEMBL7642133 0.80 SIGMAR1 (0.32) SIGMAR1HTR2AHTR6
Hydrochloric Acid SCHEMBL441994 0.79 SIGMAR1 (0.33) SIGMAR1HTR2AHTR6KDM4EMEN1
SCHEMBL439185 0.78 SIGMAR1 (0.32) SIGMAR1BRD4CCL2
SCHEMBL27688901 0.78 HTR2A (0.33) SIGMAR1HTR2AHTR6KDM4EBRD4
SCHEMBL7184249 0.78 HTR2A (0.33) SIGMAR1HTR2AHTR6KDM4EBRD4
Hydrochloric Acid SCHEMBL439186 0.77 SIGMAR1 (0.33) SIGMAR1HTR2AHTR6KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372478-B Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof 万华化学集团股份有限公司 2022-07-15 CN claimed
CN-113372478-A Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof 万华化学集团股份有限公司 2021-09-10 CN claimed
EP-1302483-B1 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts SAMSUNG ATOFINA CO LTD (KR) 2013-05-22 EP claimed
EP-2174964-B1 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts SAMSUNG GENERAL CHEMICALS CO (KR) 2013-02-20 EP claimed
EP-2174964-A2 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts Samsung General Chemicals Co., Ltd. (KR) 2010-04-14 EP claimed
EP-1302483-A2 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts Samsung General Chemicals Co., Ltd. (KR) 2003-04-16 EP claimed
US-6284701-B1 COORDINATION POLYMERIZATION CATALYSTS SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-09-04 US claimed
EP-0994132-A1 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts Samsung General Chemicals Co., Ltd. (KR) 2000-04-19 EP claimed
CN-113372478-B Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof 万华化学集团股份有限公司 2022-07-15 CN disclosed
CN-113372478-A Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof 万华化学集团股份有限公司 2021-09-10 CN disclosed
EP-1302482-B1 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts SAMSUNG TOTAL PETROCHEMICALS (KR) 2015-03-11 EP disclosed
EP-1302483-B1 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts SAMSUNG ATOFINA CO LTD (KR) 2013-05-22 EP disclosed
EP-2174963-B1 Metallocene catalysts for olefin polymerization and methog of polymerizing olefins using the metallocene catalysts SAMSUNG GENERAL CHEMICALS CO (KR) 2013-02-27 EP disclosed
EP-2174964-B1 Metallocene catalysts for olefin polymerization and method of polymerizing olefins using the metallocene catalysts SAMSUNG GENERAL CHEMICALS CO (KR) 2013-02-20 EP disclosed
US-5300581-A Melting and kneading mixture of polymer particles, graft modifier and radical initiator MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-04-05 US disclosed
US-5292811-A Crystalline propylene polymer, amorphous ethylene-alpha-olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
EP-0469153-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-02-05 EP disclosed
EP-0426853-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
EP-0427567-A2 Parabolic antenna reflector and process for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
EP-0409992-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-30 EP disclosed