SCHEMBL8733906

SCHEMBL8733906

CC(C)[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
SIGMAR1 Q99720 2/20 0.31
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763485 0.87 SIGMAR1 (0.35) MEN1KMT2ASIGMAR1
SCHEMBL8408382 0.84 MEN1 (0.32) MEN1POLBKMT2AATM
SCHEMBL7935566 0.81 SLC22A2 (0.33) SLC22A2SLC22A3MEN1KMT2A
SCHEMBL7943229 0.81 SLC22A2 (0.30) SLC22A2SLC22A3
SCHEMBL7943944 0.78 HTR6 (0.30)
SCHEMBL8561321 0.78 HTR6 (0.33)
SCHEMBL7611904 0.78 CYP2D6 (0.33) SLC22A2SLC22A3POLB
SCHEMBL6916127 0.78 SLC22A2 (0.30) SLC22A2SLC22A3
Hydrochloric Acid SCHEMBL7108220 0.78 KDM4E (0.31) SLC22A2SLC22A3MEN1KMT2A
SCHEMBL7108214 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0615981-B1 Supported catalyst system, its preparation and its use in olefin polymerisation TARGOR GMBH (DE) 1998-05-06 EP claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed
US-5545829-A Process for preparing cycloolefin copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-13 US claimed
US-5545829-A Process for preparing cycloolefin copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-13 US disclosed