Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858748 | 0.82 | SIGMAR1 (0.46) | AKR1B1KDM1AMEN1KMT2ASIGMAR1 | |
| SCHEMBL12083418 | 0.78 | CYP2A6 (0.44) | SIGMAR1 | |
| SCHEMBL367096 | 0.75 | AKR1C1 (0.47) | AKR1B1KDM1AHDAC9MEN1KMT2A | |
| SCHEMBL6495897 | 0.75 | KDM1A (0.51) | AKR1B1KDM1AMEN1KMT2ASIGMAR1 | |
| SCHEMBL4862191 | 0.75 | MEN1 (0.53) | AKR1B1KDM1AMEN1KMT2ASIGMAR1 | |
| SCHEMBL4195493 | 0.75 | KDM1A (0.50) | AKR1B1KDM1AHDAC9MEN1KMT2A | |
| SCHEMBL31629514 | 0.75 | KDM1A (0.50) | AKR1B1KDM1AHDAC9MEN1KMT2A | |
| SCHEMBL21479899 | 0.75 | MEN1 (0.42) | AKR1B1KDM1AMEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL4427642 | 0.74 | KDM1A (0.50) | AKR1B1KDM1AMEN1KMT2ASIGMAR1 | |
| SCHEMBL11393939 | 0.74 | KDM1A (0.46) | AKR1B1KDM1AHDAC9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100422181-C | [1,8] naphthyridin-2-ones and related compounds for the treatment of schizophrenia | WARNER LAMBERT CO (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-1839134-A | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia | WARNER LAMBERT CO (US) | 2006-09-27 | — | — | CN | disclosed |