Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366905 | 0.75 | AR (0.36) | ARL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL27656351 | 0.68 | FAAH (0.39) | FAAHL3MBTL1TDP1KCNA3KCNA5 | |
| SCHEMBL713499 | 0.68 | TSHR (0.50) | L3MBTL1TDP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL4288063 | 0.68 | L3MBTL1 (0.40) | ARL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL2640223 | 0.67 | TSHR (0.70) | L3MBTL1TDP1KCNA3HRH4HRH3 | |
| SCHEMBL711369 | 0.67 | L3MBTL1 (0.50) | L3MBTL1TDP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL18585071 | 0.67 | L3MBTL1 (0.50) | L3MBTL1TDP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL6211503 | 0.67 | L3MBTL1 (0.50) | L3MBTL1TDP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL5561948 | 0.67 | L3MBTL1 (0.50) | L3MBTL1TDP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL1009942 | 0.67 | L3MBTL1 (0.50) | L3MBTL1TDP1SMN1; SMN2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100422181-C | [1,8] naphthyridin-2-ones and related compounds for the treatment of schizophrenia | WARNER LAMBERT CO (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-1839134-A | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia | WARNER LAMBERT CO (US) | 2006-09-27 | — | — | CN | disclosed |