Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875114 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL1009942 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL7784378 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL5561948 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL18585071 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL711369 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL27274855 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL6211503 | 0.98 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL710282 | 0.94 | TSHR (0.52) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL6263416 | 0.94 | TSHR (0.52) | TSHRL3MBTL1TDP1TEAD3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58152829-A | — | — | None | — | — | JP | disclosed |
| JP-3123780-A | — | — | None | — | — | JP | disclosed |
| US-12559486-B2 | Tau-protein targeting compounds and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| EP-4688790-A1 | MACROCYCLIC RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20260028353-A1 | MACROCYCLIC RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2026-01-29 | — | — | US | disclosed |
| EP-3681875-B1 | CYCLIC PEPTIDE ANTIBIOTICS | HOFFMANN LA ROCHE (CH) | 2026-01-14 | — | — | EP | disclosed |
| CN-111148739-B | Cyclic peptide antibiotics | 豪夫迈·罗氏有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119630672-A | Camptothecin derivative and conjugate thereof, and preparation method and medical application thereof | 一线医药（杭州）有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| EP-0367747-B1 | Dideoxy-L-arabinitol derivatives as antiviral compounds | SEARLE & CO (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1995022966-A1 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP, INC. (US) | 1995-08-31 | — | — | WO | disclosed |
| US-5248810-A | Insecticides, acaricides | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-28 | — | — | US | disclosed |
| US-5081287-A | Pesticidal polyhalo alkenoic acid esters | FMC CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0432861-A1 | Halogenated olefines, process for the preparation thereof and their use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-19 | — | — | EP | disclosed |
| JP-H03123780-A | 2H-BENZO(B)QUINOLIDINE DERIVATIVE | SAGAMI CHEM RES CENTER | 1991-05-27 | — | — | JP | disclosed |
| US-4973602-A | N-ARYL DERIVATIVE OF 1,4-DIDEOXY-1,4-IMINO-L-ARAINITOL | G. D. SEARLE & CO. (US) | 1990-11-27 | — | — | US | disclosed |
| US-4937357-A | ACYLATED DERIVATIVES OF 1,4-DIDEOXY-1,4-IMINO-L-ARABINOL | G. D. SEARLE & CO. (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0367747-A2 | Dideoxy-L-arabinitol derivatives as antiviral compounds | G.D. Searle & Co. (US) | 1990-05-09 | — | — | EP | disclosed |
| JP-S58152829-A | 1,2,3,7,8,8A-HEXAHYDRO-1-HYDROXY-7-METHYL-8-(3'-HYDROXY) PROPYLNAPHTHALENE | SUNTORY LTD | 1983-09-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028353-A1 | MACROCYCLIC RAS INHIBITORS | KRAS, NRAS, HRAS | TSHR 1913/4885L3MBTL1 4000/4885TDP1 4464/4885 |
| US-12559486-B2 | Tau-protein targeting compounds and associated methods of use | UBQLN2, UBQLN1, CRBN | TSHR 2915/4885L3MBTL1 539/4885TDP1 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.