Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | CTSV | O60911 | 4/20 | 0.57 |
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28759917 | 0.80 | NPC1 (0.45) | KDM4ECTSVCTSLNPSR1HSD17B10 | |
| SCHEMBL28633752 | 0.80 | KDR (0.56) | KDM4EHPGDNPSR1HSD17B10LMNA | |
| SCHEMBL924438 | 0.78 | ESR1 (0.71) | KDM4EHPGDNPSR1HSD17B10LMNA | |
| SCHEMBL8787406 | 0.77 | ALDH1A1 (0.51) | KDM4EHPGDNPSR1HSD17B10LMNA | |
| SCHEMBL4497587 | 0.74 | TNKS (0.59) | KDM4EHPGDHSD17B10LMNAALDH1A1 | |
| SCHEMBL8786762 | 0.74 | NPC1 (0.54) | KDM4EHPGDNPSR1HSD17B10LMNA | |
| SCHEMBL27635444 | 0.74 | HPGD (0.51) | KDM4ECTSVCTSLHPGDNPSR1 | |
| SCHEMBL7256021 | 0.73 | ESR1 (0.54) | KDM4ECTSVCTSLHPGDNPSR1 | |
| SCHEMBL30561047 | 0.73 | NPC1 (1.00) | KDM4EHPGDNPSR1HSD17B10LMNA | |
| SCHEMBL30634854 | 0.73 | NPC1 (1.00) | KDM4EHPGDNPSR1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100488960-C | 2-substituted quinolone compound and use in pharmacy | UNIV CHINA PHARMA (CN) | 2009-05-20 | — | — | CN | disclosed |
| CN-1817880-A | 2-bit-substituted quinolone compound and use in pharmacey | UNIV CHINA PHARMA (CN) | 2006-08-16 | — | — | CN | disclosed |