Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 3/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4497587 | 0.82 | TNKS (0.59) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL924438 | 0.80 | ESR1 (0.71) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL27635441 | 0.80 | KDM4E (0.57) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL27824964 | 0.76 | ALDH1A1 (0.62) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL21297858 | 0.74 | HPGD (0.63) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL7256021 | 0.72 | ESR1 (0.54) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL30305373 | 0.72 | KDR (0.78) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL3503147 | 0.72 | KDR (1.00) | KDRFGFR1PDGFRBNPC1RAB9A | |
| SCHEMBL30561047 | 0.72 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL172216 | 0.72 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181214-A | Non-activated alkane C (sp)3) -H-functional initiated radical cyclization reaction process | 宁波大学 | 2022-03-15 | — | — | CN | claimed |
| CN-113373465-B | Method for synthesizing silicon-based substituted benzimidazolo isoquinolinone compounds through photoelectric concerted catalysis | 北京工业大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114181214-A | Non-activated alkane C (sp)3) -H-functional initiated radical cyclization reaction process | 宁波大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-114181214-A | Non-activated alkane C (sp)3) -H-functional initiated radical cyclization reaction process | 宁波大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-113980016-A | Method for preparing benzimidazol isoquinolinone compound | 怀化学院 | 2022-01-28 | — | — | CN | disclosed |
| CN-113373465-A | Method for synthesizing silicon-based substituted benzimidazolo isoquinolinone compounds through photoelectric concerted catalysis | 北京工业大学 | 2021-09-10 | — | — | CN | disclosed |