Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700556 | 0.92 | ADH1A (0.31) | ADH1AADH1C | |
| SCHEMBL9700534 | 0.89 | CYP1A2 (0.36) | ADH1ACYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27739124 | 0.83 | CYP2D6 (0.34) | ADH1AADH1CCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL27799995 | 0.81 | FDPS (0.32) | CYP2D6SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL16716038 | 0.73 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL25838712 | 0.72 | CYP2D6 (0.33) | ADH1AADH1CCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8809955 | 0.69 | CYP1A2 (0.31) | CYP2D6CYP1A2 | |
| SCHEMBL11073680 | 0.69 | ADH1A (0.54) | ADH1AADH1CFYNHTR1A | |
| SCHEMBL22541111 | 0.69 | ADH1A (0.54) | ADH1AADH1CFYNHTR1A | |
| SCHEMBL516269 | 0.69 | ADH1A (0.54) | ADH1AADH1CFYNHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1711260-A | Pyridopyrimidinone compounds, process for their preparation and medicaments containing them | SERVIER LAB (FR) | 2005-12-21 | — | — | CN | disclosed |