SCHEMBL2763620

SCHEMBL2763620

COC1(C)c2cc(Br)ccc2-c2ccc(Br)cc2C1(OC)c1ccc(C)cc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
APP P05067 1/20 0.32
PDK2 Q15119 1/20 0.31
MAOB P27338 1/20 0.31
MAPT P10636 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
GAA P10253 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2764629 0.83 PDK2 (0.36) ALDH1A1APPPDK2MAPTMEN1
SCHEMBL2487230 0.79 PDK2 (0.40) ALDH1A1APPPDK2MAPK1
SCHEMBL2487352 0.79 PDK2 (0.40) ALDH1A1APPPDK2MAPK1
SCHEMBL2764075 0.74 MEN1 (0.35) ALDH1A1PDK2MAPTKDM4EMEN1
SCHEMBL13567251 0.73 ALDH1A1 (0.44) ALDH1A1APPPDK2MAPTKDM4E
SCHEMBL12669181 0.70 PDK2 (0.42) ALDH1A1PDK2MAPTKDM4EMEN1
SCHEMBL14226935 0.69 ALDH1A1 (0.36) ALDH1A1PDK2
SCHEMBL15552689 0.69 PDK2 (0.45) ALDH1A1PDK2MAPTMAPK1
SCHEMBL10358919 0.69 ALDH1A1 (0.36) ALDH1A1PDK2
SCHEMBL2484075 0.68 PDK2 (0.37) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723455-B2 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2010-05-25 US disclosed
US-7723455-B2 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2010-05-25 US disclosed
US-7723455-B2 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2010-05-25 US disclosed
EP-1656408-B1 CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF MERCK PATENT GMBH (DE) 2010-04-14 EP disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 US disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 US disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 US disclosed
EP-1656408-A2 CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF Covion Organic Semiconductors GmbH (DE) 2006-05-17 EP disclosed
WO-2005014689-A2 CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2005-02-17 WO disclosed