SCHEMBL2764075

SCHEMBL2764075

COC1(c2ccc(C(C)(C)C)cc2)c2cc(Br)ccc2-c2ccc(Br)cc2C1(OC)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PDK2 Q15119 1/20 0.35
WDR5 P61964 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
NR1I2 O75469 1/20 0.31
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13475615 0.89 MEN1 (0.37) MEN1KMT2ASMN1; SMN2PDK2
SCHEMBL20198314 0.80
SCHEMBL2763690 0.80 PDK2 (0.44) MEN1KMT2ASMN1; SMN2PDK2WDR5
SCHEMBL13708952 0.77 KIF11 (0.37) MEN1KMT2ASMN1; SMN2PDK2KDM4E
SCHEMBL18561058 0.76 PDK2 (0.37) PDK2ALDH1A1MAPTNR1I2
SCHEMBL13709017 0.76 PDK2 (0.41) MEN1KMT2ASMN1; SMN2PDK2KDM4E
SCHEMBL2764074 0.75 PDK2 (0.43) PDK2ALDH1A1
SCHEMBL25596251 0.75 PDK2 (0.47) MEN1KMT2ASMN1; SMN2PDK2KDM4E
SCHEMBL4405161 0.74
SCHEMBL22745012 0.74 PDK2 (0.40) MEN1KMT2ASMN1; SMN2PDK2WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1794218-B1 ELECTRONIC DEVICES CONTAINING ORGANIC SEMI-CONDUCTORS MERCK PATENT GMBH (DE) 2020-05-13 EP disclosed
US-9150687-B2 Electronic devices containing organic semi-conductors MERCK PATENT GMBH (DE) 2015-10-06 US disclosed
US-9150687-B2 Electronic devices containing organic semi-conductors MERCK PATENT GMBH (DE) 2015-10-06 US disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-8044217-B2 White-emitting copolymers, representation, and use thereof MERCK PATENT GMBH (DE) 2011-10-25 US disclosed
US-8044217-B2 White-emitting copolymers, representation, and use thereof MERCK PATENT GMBH (DE) 2011-10-25 US disclosed
EP-2366752-A2 New materials for electroluminescence and use of same Merck Patent GmbH (DE) 2011-09-21 EP disclosed
US-20100197875-A1 WHITE-EMITTING COPOLYMERS, REPRESENTATION, AND USE THEREOF MERCK PATENT GMBH (DE) 2010-08-05 US disclosed
US-20100197875-A1 WHITE-EMITTING COPOLYMERS, REPRESENTATION, AND USE THEREOF MERCK PATENT GMBH (DE) 2010-08-05 US disclosed
EP-1656408-B1 CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF MERCK PATENT GMBH (DE) 2010-04-14 EP disclosed
US-7696284-B2 White-emitting copolymers, representation and use thereof MERCK PATENT GMBH (DE) 2010-04-13 US disclosed
US-7696284-B2 White-emitting copolymers, representation and use thereof MERCK PATENT GMBH (DE) 2010-04-13 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20080113468-A1 Polymer selected from poly-p-arylenevinylenes, polyfluorenes, poly-spiro-bifluorenes, poly-para-phenylenes, biphenylenes, polydihydrophenanthrenes; lifetime, efficiency MERCK PATENT GMBH (DE) 2008-05-15 US disclosed
US-20080113468-A1 Polymer selected from poly-p-arylenevinylenes, polyfluorenes, poly-spiro-bifluorenes, poly-para-phenylenes, biphenylenes, polydihydrophenanthrenes; lifetime, efficiency MERCK PATENT GMBH (DE) 2008-05-15 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 US disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 US disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197875-A1 WHITE-EMITTING COPOLYMERS, REPRESENTATION, AND USE THEREOF IK, MAP1LC3A, MAP1LC3C MEN1 4733/4885KMT2A 1622/4885SMN1; SMN2 3062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.