Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763620 | 0.83 | ALDH1A1 (0.33) | PDK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2487230 | 0.79 | PDK2 (0.40) | PDK2ALDH1A1LMNACA1CA2 | |
| SCHEMBL2487352 | 0.79 | PDK2 (0.40) | PDK2ALDH1A1LMNACA1CA2 | |
| SCHEMBL12669181 | 0.77 | PDK2 (0.42) | PDK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14877472 | 0.73 | ALDH1A1 (0.41) | PDK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13567251 | 0.73 | ALDH1A1 (0.44) | PDK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23221362 | 0.72 | PDK2 (0.44) | PDK2ALDH1A1MAPTLMNACA1 | |
| SCHEMBL22071209 | 0.71 | PDK2 (0.51) | PDK2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL12669173 | 0.70 | ACHE (0.42) | PDK2ALDH1A1CA1CA2CA4 | |
| SCHEMBL14226935 | 0.69 | ALDH1A1 (0.36) | PDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723455-B2 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1656408-B1 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-04-14 | — | — | EP | disclosed |
| US-20070060736-A1 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |
| EP-1656408-A2 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005014689-A2 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-02-17 | — | — | WO | disclosed |