Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636264 | 0.84 | TACR1 (0.32) | — | |
| SCHEMBL30442907 | 0.80 | ALDH1A1 (0.36) | IDO1TDO2SLC6A2SLC6A4GLS | |
| SCHEMBL20746911 | 0.76 | CYP1A2 (0.45) | IDO1TDO2LMNA | |
| SCHEMBL23169104 | 0.76 | CYP1A2 (0.45) | IDO1TDO2LMNA | |
| SCHEMBL20072419 | 0.75 | CYP1A2 (0.44) | IDO1TDO2LMNA | |
| SCHEMBL4628953 | 0.71 | TAAR1 (0.47) | IDO1 | |
| SCHEMBL21142421 | 0.70 | CYP2D6 (0.40) | IDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL27636258 | 0.70 | IDO1 (0.41) | IDO1TDO2SLC6A2SLC6A4MGAM | |
| SCHEMBL22306322 | 0.69 | IDO1 (0.41) | IDO1TDO2SLC6A2SLC6A4GAA | |
| SCHEMBL27410794 | 0.68 | RIPK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1732152-A | Phenylethanolamine derivatives for the treatment of respiratory diseases | GLAXO GROUP LTD (GB) | 2006-02-08 | — | — | CN | disclosed |