Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899776 | 0.70 | IDO1 (0.42) | IDO1TDO2SIGMAR1SLC6A4HTR2A | |
| SCHEMBL7784138 | 0.70 | HRH1 (0.58) | SIGMAR1SLC6A2SLC6A4HTR2AHRH1 | |
| SCHEMBL2093300 | 0.70 | IDO1 (0.43) | IDO1TDO2MGAMGAASI | |
| SCHEMBL27636259 | 0.70 | IDO1 (0.36) | IDO1TDO2MGAMGAASI | |
| SCHEMBL8120556 | 0.69 | SIGMAR1 (0.46) | IDO1TDO2SIGMAR1CTSAHTR2A | |
| SCHEMBL28483704 | 0.68 | IDO1 (0.42) | IDO1TDO2SLC18A3SIGMAR1SLC6A2 | |
| SCHEMBL6003039 | 0.68 | IDO1 (0.42) | IDO1TDO2CTSA | |
| SCHEMBL11394543 | 0.68 | IDO1 (0.50) | IDO1TDO2HTR2AHRH1TACR1 | |
| SCHEMBL17295946 | 0.64 | IDO1 (0.49) | IDO1TDO2MGAMGAASI | |
| SCHEMBL3939237 | 0.64 | IDO1 (0.49) | IDO1TDO2MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1732152-A | Phenylethanolamine derivatives for the treatment of respiratory diseases | GLAXO GROUP LTD (GB) | 2006-02-08 | — | — | CN | disclosed |