Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14032871 | 0.90 | CYP1A2 (0.40) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL5103655 | 0.88 | CYP1A2 (0.39) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL31252127 | 0.84 | ALDH1A1 (0.44) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL31252203 | 0.83 | PRKCA (0.41) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL27988047 | 0.82 | KDM4E (0.36) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL7848701 | 0.81 | ALDH1A1 (0.48) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL5097106 | 0.81 | CYP1A2 (0.41) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL16877111 | 0.80 | GAA (0.43) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL5109822 | 0.80 | CYP1A2 (0.44) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL7848700 | 0.80 | GAA (0.46) | GAAMGAMSIMGAM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100381438-C | New pyrrolidine and thiazolidine compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2008-04-16 | — | — | CN | disclosed |
| CN-1721417-A | New pyrrolidine and thiazolidine compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2006-01-18 | — | — | CN | disclosed |