Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16598868 | 0.82 | ALDH1A1 (0.47) | SIGMAR1MEN1ALDH1A1CYP2C9KMT2A | |
| SCHEMBL16598932 | 0.78 | SIGMAR1 (0.51) | SIGMAR1KMT2ACYP2D6ADRB1 | |
| SCHEMBL16598812 | 0.78 | HPGD (0.40) | SIGMAR1MEN1ALDH1A1KMT2AHTR3A | |
| SCHEMBL2228270 | 0.76 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MC4RDRD4 | |
| SCHEMBL16599267 | 0.75 | DBH (0.36) | ALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16598887 | 0.75 | TACR1 (0.35) | SIGMAR1MEN1KMT2ACXCR4ADRB1 | |
| SCHEMBL4903098 | 0.75 | ALDH1A1 (0.46) | SIGMAR1MEN1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL4906727 | 0.73 | MAPT (0.40) | MEN1ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL6138636 | 0.72 | SIGMAR1 (1.00) | SIGMAR1MEN1ALDH1A1CYP2C9TSHR | |
| SCHEMBL152631 | 0.72 | SIGMAR1 (1.00) | SIGMAR1MEN1ALDH1A1CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125997-A | Pterocarpus stilbene paeonol chalcone amide derivative, preparation method and medical application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-116102565-A | Isolamine-containing spirochromone compound and preparation method and application thereof | 贵州大学 | 2023-05-12 | — | — | CN | claimed |
| CN-113717201-B | (+/-) -Marinopyrole A derivative and preparation method and application thereof | 植恩生物技术股份有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-115260046-A | Abietate compound and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | claimed |
| CN-115141208-A | Podophyllotoxin compound containing various ester group structures and preparation method and application thereof | 贵州大学 | 2022-10-04 | — | — | CN | claimed |
| CN-114920722-A | 7-hydroxy-3-acetyl coumarin oxime compound, preparation method and medical application thereof | 何黎琴 | 2022-08-19 | — | — | CN | claimed |
| CN-113717201-A | (+/-) -Marinopyrole A derivative and preparation method and application thereof | 植恩生物技术股份有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-112707843-A | Novel paeonol oxime compound, preparation method and medical application thereof | 何黎琴 | 2021-04-27 | — | — | CN | claimed |
| CN-112624931-A | Pterostilbene amine compounds containing isopropanol aromatic ether structure and preparation method and application thereof | 贵州大学 | 2021-04-09 | — | — | CN | claimed |
| EP-0567982-B1 | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-01 | — | — | EP | claimed |
| EP-0804428-A1 | BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | claimed |
| EP-0347678-B1 | 1,4-Dihydropyridine threonin derivatives and process for their preparation | BAYER AG (DE) | 1997-02-26 | — | — | EP | claimed |
| US-5604294-A | IMMUNOSUPRESSIVE, ANTIMICROBIAL, ANTIFUNGAL, ANTIVIRAL, ANTI-INFLAMMATORY AND ANTIPROLIFERATIVE ACTIVITY | ABBOTT LABORATORIES | 1997-02-18 | — | — | US | claimed |
| WO-1996022287-A1 | BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | claimed |
| WO-1994021635-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | claimed |
| US-4939142-A | Substituted styrene derivatives | EGIS GYOGYSZERGYAR (HU) | 1990-07-03 | — | — | US | claimed |
| EP-0347678-A2 | 1,4-Dihydropyridine threonin derivatives and process for their preparation | BAYER AG (DE) | 1989-12-27 | — | — | EP | claimed |
| US-4786638-A | TREATMENT OR PREVENTION OF DIABETIC COMPLICATIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-11-22 | — | — | US | claimed |
| US-4395413-A | NICOTINE ANTIALLERGEN, ANESTHETIC, ANALGESIC, HYPOTENSIVE, AND ANTIULCER AGENT | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-07-26 | — | — | US | claimed |