SCHEMBL27636718

SCHEMBL27636718

Cc1c(C)c(C(C)C)c(C)c(O)c1O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 2/20 0.33
MCL1 Q07820 2/20 0.33
BCL2L1 Q07817 1/20 0.33
BCL2L2 Q92843 1/20 0.33
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
FAAH O00519 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRA1 P14867 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526052 0.91 BCL2 (0.34) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL23943247 0.86 LDHA (0.35) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL14201680 0.86 LDHA (0.35) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL19972877 0.82 BCL2 (0.33) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL19183569 0.80 BCL2 (0.32) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL9070220 0.79 BCL2 (0.34) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL4967470 0.79 BCL2 (0.34) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL1242989 0.78 BCL2 (0.35) BCL2MCL1BCL2L1BCL2L2LDHA
SCHEMBL8330118 0.77
SCHEMBL19020514 0.77 LDHA (0.36) BCL2MCL1BCL2L1BCL2L2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101935512-B Reactive hot melt adhesive with improved hydrolysis resistance HENKEL AG & CO KGAA 2013-01-02 CN claimed
CN-101935512-A Reactive hot melt adhesive with improved hydrolysis resistance NAT STARCH CHEM INVEST 2011-01-05 CN claimed
CN-1829784-B Reactive hot melt adhesive with improved hydrolysis resistance NAT STARCH CHEM INVEST 2010-12-01 CN claimed
CN-1829784-A Reactive hot melt adhesive with improved hydrolysis resistance NAT STARCH CHEM INVEST (US) 2006-09-06 CN claimed
CN-101935512-B Reactive hot melt adhesive with improved hydrolysis resistance HENKEL AG & CO KGAA 2013-01-02 CN disclosed
CN-101935512-A Reactive hot melt adhesive with improved hydrolysis resistance NAT STARCH CHEM INVEST 2011-01-05 CN disclosed
CN-1829784-B Reactive hot melt adhesive with improved hydrolysis resistance NAT STARCH CHEM INVEST 2010-12-01 CN disclosed
CN-1829784-A Reactive hot melt adhesive with improved hydrolysis resistance NAT STARCH CHEM INVEST (US) 2006-09-06 CN disclosed