Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894457 | 0.83 | CHRM3 (0.58) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL8892547 | 0.80 | DRD2 (0.57) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL13552272 | 0.80 | CHRM3 (0.54) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL8891819 | 0.80 | DRD2 (0.62) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL8673178 | 0.78 | DRD2 (0.53) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL9406032 | 0.78 | MTNR1A (0.71) | CHRM3CHRM2CHRM1CYP1A2CA1 | |
| SCHEMBL266906 | 0.77 | DRD2 (0.74) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL5585108 | 0.77 | DRD2 (0.80) | DRD2DRD3HTR1AHTR7HTR1D | |
| Hydrochloric Acid SCHEMBL7926395 | 0.77 | DRD2 (0.52) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL27341732 | 0.77 | MTNR1A (0.51) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101808646-A | Agent for improving motor complications or mental symptoms of Parkinson's disease | ASUBIO PHARMA CO LTD | 2010-08-18 | — | — | CN | disclosed |
| CN-1708302-A | Pharmacological treatment of sleep apnea | UNIV ILLINOIS (US) | 2005-12-14 | — | — | CN | disclosed |