Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | HTR1B | P28222 | 4/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19179854 | 0.84 | HSD11B1 (0.56) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL1748180 | 0.81 | HSD11B1 (0.56) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL3362412 | 0.79 | HSD11B1 (0.55) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL27351302 | 0.78 | HSD11B1 (0.56) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL18097828 | 0.78 | HSD11B1 (0.56) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL3904794 | 0.75 | HSD11B1 (0.43) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL5565709 | 0.73 | ALDH1A1 (0.51) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL20526582 | 0.73 | HTR1D (0.46) | HSD11B1HTR1DHTR1AHTR1BCA1 | |
| SCHEMBL6284793 | 0.72 | CXCR2 (0.43) | HSD11B1HTR1DHTR1AHTR1BCXCR2 | |
| SCHEMBL5569165 | 0.72 | HSD11B1 (0.47) | HSD11B1HTR1DCXCR2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816531-A | Process for the preparation of aryl alkyl acid derivatives and their use for the treatment of obesity | BAYER PHARMACEUTICALS CORP (US) | 2006-08-09 | — | — | CN | disclosed |