Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29139504 | 0.88 | BRD4 (0.30) | — | |
| SCHEMBL22283801 | 0.87 | GLA (0.32) | GLA | |
| Hydrochloric Acid SCHEMBL27275362 | 0.80 | MMP2 (0.31) | — | |
| SCHEMBL27637686 | 0.79 | RIPK1 (0.32) | — | |
| SCHEMBL5036518 | 0.76 | ESR2 (0.33) | — | |
| SCHEMBL7782039 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL6561822 | 0.73 | — | — | |
| SCHEMBL28546737 | 0.72 | HSP90AA1 (0.31) | — | |
| SCHEMBL27837998 | 0.72 | PIK3CD (0.38) | — | |
| SCHEMBL31591139 | 0.71 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292479-B | Preparation method of 5-azaspiro [2.4] heptane and salt thereof | 南京合巨药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-113292479-A | Preparation method of 5-azaspiro [2.4] heptane and salt thereof | 南京合巨药业有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-103748087-A | Indazole- and pyrrolopyridine-derivative and pharmaceutical use thereof | DAINIPPON SUMITOMO PHARMA CO | 2014-04-23 | — | — | CN | disclosed |
| CN-101289445-A | Aniline quinazoline derivatives, preparation method and uses thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2008-10-22 | — | — | CN | disclosed |