Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658887 | 0.90 | ALDH1A1 (0.44) | GAATSHRPOLBNFKB1TDP1 | |
| SCHEMBL27775230 | 0.82 | MAPT (0.44) | GAATSHRPOLBTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL27795960 | 0.81 | MAPT (0.43) | GAATSHRPOLBTDP1KDM4E | |
| SCHEMBL27627920 | 0.79 | ALDH1A1 (0.43) | GAAPOLBKDM4ELMNAMAPT | |
| SCHEMBL3328720 | 0.79 | IGFBP5 (0.50) | ELANETSHRPOLBLMNATRPA1 | |
| SCHEMBL27311485 | 0.79 | MEN1 (0.48) | GAATDP1KDM4EHPGDHSD17B10 | |
| SCHEMBL2908954 | 0.74 | ELANE (0.43) | ELANETSHRKDM4EHSD17B10TRPA1 | |
| SCHEMBL6299614 | 0.74 | HSD17B10 (0.38) | GAAELANETSHRPOLBNFKB1 | |
| SCHEMBL14093025 | 0.70 | TRPA1 (0.55) | GAATSHRPOLBNFKB1TDP1 | |
| SCHEMBL12463923 | 0.70 | ELANE (0.41) | GAAELANEPOLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1835944-A | Quinolyl amide derivatives as CCR-5 antagonists | SCHERING AG (DE) | 2006-09-20 | — | — | CN | disclosed |