SCHEMBL2763848

SCHEMBL2763848

COC(=O)[C@@H](N)CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 1/20 0.32
KIF11 P52732 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10679170 1.00 BTN3A1 (0.32) BTN3A1KIF11CA1CA2
SCHEMBL3616995 1.00 BTN3A1 (0.32) BTN3A1KIF11CA1CA2
SCHEMBL4217873 0.86 NOS1 (0.33) BTN3A1
SCHEMBL30980082 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL19699429 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL1067509 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL1067514 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL20591675 0.81 NOS3 (0.38) KIF11
SCHEMBL21224417 0.81
SCHEMBL21224419 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312349-B2 Apoptosis-inducing agents FOCHON PHARMACEUTICALS, LTD. (CN) 2025-05-27 US disclosed
EP-4119560-B1 APOPTOSIS-INDUCING AGENTS FOCHON PHARMACEUTICALS LTD (CN) 2024-06-05 EP disclosed
EP-4335512-A2 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS HiberCell, Inc. (US) 2024-03-13 EP disclosed
EP-3728217-B1 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS HIBERCELL INC (US) 2023-11-15 EP disclosed
EP-3728217-B1 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS HIBERCELL INC (US) 2023-11-15 EP disclosed
CN-116589459-A Apoptosis inducer 重庆复创医药研究有限公司 2023-08-15 CN disclosed
CN-110546151-B Apoptosis inducer 重庆复创医药研究有限公司 2023-04-28 CN disclosed
US-11584763-B2 Chromenopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors HIBERCELL, INC. (US) 2023-02-21 US disclosed
US-11584763-B2 Chromenopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors HIBERCELL, INC. (US) 2023-02-21 US disclosed
EP-4119560-A1 APOPTOSIS-INDUCING AGENTS Shanghai Fochon Pharmaceutical Co., Ltd. (CN) 2023-01-18 EP disclosed
CN-1938301-A Tetrahydronaphthyridine derivatives as cholesteryl ester transfer protein inhibitors TANABE SEIYAKU CO (JP) 2007-03-28 CN disclosed
US-20070032485-A1 Tetrahydronaphthyridine derivatives and a process for preparing the same TANABE SEIYAKU CO., LTD. 2007-02-08 US disclosed
EP-1732924-A2 TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 2006-12-20 EP disclosed
WO-2005095395-A2 TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 2005-10-13 WO disclosed
EP-1400515-A1 CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP Kowa Co., Ltd. (JP) 2004-03-24 EP disclosed
EP-0900211-B1 THIADIAZOLYL(THIO)UREAS USEFUL AS MATRIX METALLOPROTEASE INHIBITORS UPJOHN CO (US) 2003-07-02 EP disclosed
US-6472386-B1 Cyclic diamine compound with 5-membered ring groups KOWA CO., LTD. (JP) 2002-10-29 US disclosed
US-5847148-A Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation PHARMACIA & UPJOHN COMPANY (US) 1998-12-08 US disclosed
US-4751299-A Optically active β-lactams and method of their production TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-06-14 US disclosed
EP-0144840-A2 Optically active beta-lactams and method of their production Takeda Chemical Industries, Ltd. (JP) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12312349-B2 Apoptosis-inducing agents BCL2, BAX, BAD BTN3A1 3476/4885KIF11 4485/4885CA1 2744/4885
US-11584763-B2 Chromenopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors PIP5K1A, PIP5K1B, PI4KA BTN3A1 3530/4885KIF11 4287/4885CA1 4295/4885
US-20070032485-A1 Tetrahydronaphthyridine derivatives and a process for preparing the same CETP, MTTP, NPC1L1 BTN3A1 3958/4885KIF11 2027/4885CA1 4813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.