SCHEMBL10679170

SCHEMBL10679170

COC(=O)[C@H](N)CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 1/20 0.32
KIF11 P52732 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763848 1.00 BTN3A1 (0.32) BTN3A1KIF11CA1CA2
SCHEMBL3616995 1.00 BTN3A1 (0.32) BTN3A1KIF11CA1CA2
SCHEMBL4217873 0.86 NOS1 (0.33) BTN3A1
SCHEMBL30980082 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL19699429 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL1067509 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL1067514 0.83 IDO1 (0.34) BTN3A1KIF11CA1CA2
SCHEMBL20591675 0.81 NOS3 (0.38) KIF11
SCHEMBL21224417 0.81
SCHEMBL21224419 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4039257-B1 PHARMACEUTICAL COMPOSITION AND KIT CONTAINING A PENAM DERIVATIVE OR SALT THEREOF AND ONE OR MORE COMPOUNDS SELECTED FROM BETA-LACTAMASE INHIBITOR COMPOUND, ANTIBACTERIAL COMPOUND AND SALTS OF THESE FUJIFILM CORP (JP) 2026-05-27 EP disclosed
US-12312349-B2 Apoptosis-inducing agents FOCHON PHARMACEUTICALS, LTD. (CN) 2025-05-27 US disclosed
US-12286440-B2 Penam derivative or salt thereof, pharmaceutical composition, and applications thereof FUJIFILM CORPORATION (JP) 2025-04-29 US disclosed
CN-114531850-B Pharmaceutical composition and kit characterized by containing novel penicillin derivative or salt thereof and at least 1 compound selected from beta-lactamase inhibitory compound and antibacterial compound or salt thereof 富士胶片株式会社 2024-08-06 CN disclosed
EP-4119560-B1 APOPTOSIS-INDUCING AGENTS FOCHON PHARMACEUTICALS LTD (CN) 2024-06-05 EP disclosed
CN-111954673-B New penam derivatives or salts thereof, pharmaceutical compositions and uses thereof 富士胶片株式会社 2023-09-05 CN disclosed
CN-116589459-A Apoptosis inducer 重庆复创医药研究有限公司 2023-08-15 CN disclosed
WO-2023098831-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM 嘉兴优博生物技术有限公司 2023-06-08 WO disclosed
CN-110546151-B Apoptosis inducer 重庆复创医药研究有限公司 2023-04-28 CN disclosed
EP-4119560-A1 APOPTOSIS-INDUCING AGENTS Shanghai Fochon Pharmaceutical Co., Ltd. (CN) 2023-01-18 EP disclosed
WO-2021066149-A1 PHARMACEUTICAL COMPOSITION AND KIT CHARACTERIZED BY CONTAINING NOVEL PENAM DERIVATIVE OR SALT THEREOF AND ONE OR MORE COMPOUNDS SELECTED FROM Β-LACTAMASE INHIBITOR COMPOUND, ANTIBACTERIAL COMPOUND AND SALTS OF THESE 富士フイルム株式会社 2021-04-08 WO disclosed
EP-3778609-A1 NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF FUJIFILM Corporation (JP) 2021-02-17 EP disclosed
US-20210024543-A1 NOVEL PENAM DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF FUJIFILM CORPORATION (JP) 2021-01-28 US disclosed
US-20210024543-A1 NOVEL PENAM DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF FUJIFILM CORPORATION (JP) 2021-01-28 US disclosed
CN-111954673-A Novel penam derivative or salt thereof, pharmaceutical composition, and use thereof 富士胶片株式会社 2020-11-17 CN disclosed
US-20200115379-A1 APOPTOSIS-INDUCING AGENTS FOCHON PHARMACEUTICALS, LTD. (CN) 2020-04-16 US disclosed
CN-110546151-A apoptosis-inducing agent SHANGHAI FOCHON PHARMACEUTICAL CO LTD 2019-12-06 CN disclosed
WO-2019194306-A1 NOVEL PENAM DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF 富士フイルム株式会社 2019-10-10 WO disclosed
US-4751299-A Optically active β-lactams and method of their production TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-06-14 US disclosed
EP-0144840-A2 Optically active beta-lactams and method of their production Takeda Chemical Industries, Ltd. (JP) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12312349-B2 Apoptosis-inducing agents BCL2, BAX, BAD BTN3A1 3476/4885KIF11 4485/4885CA1 2744/4885
US-20200115379-A1 APOPTOSIS-INDUCING AGENTS BCL2, BAX, BAD BTN3A1 3476/4885KIF11 4485/4885CA1 2744/4885
US-20210024543-A1 NOVEL PENAM DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF CFTR, SLC11A2, SLC20A1 BTN3A1 3879/4885KIF11 2569/4885CA1 4736/4885
US-12286440-B2 Penam derivative or salt thereof, pharmaceutical composition, and applications thereof CFTR, SLC11A2, REN BTN3A1 3681/4885KIF11 2689/4885CA1 4681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.