Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681424 | 0.80 | KMT2A (0.50) | LMNAKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL4298832 | 0.68 | KMT2A (0.40) | LMNAKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL1681425 | 0.68 | KMT2A (0.40) | LMNAKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL13516238 | 0.66 | PPARA (0.42) | — | |
| SCHEMBL13130618 | 0.66 | KMT2A (0.56) | LMNAKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL569625 | 0.64 | LMNA (0.43) | LMNAKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL4137634 | 0.63 | ALOX15 (0.40) | LMNAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6770448 | 0.63 | KMT2A (0.49) | LMNAKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL6770445 | 0.63 | KMT2A (0.49) | LMNAKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL7931858 | 0.62 | PPARA (0.39) | KMT2AMAPTMEN1MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863793-A | Cyclic tertiary amine compound | SANKYO CO (JP) | 2006-11-15 | — | — | CN | disclosed |