Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8532842 | 0.97 | LMNA (0.41) | LMNAALDH1A3KMT2AMAPTNPSR1 | |
| Ethylene Glycol SCHEMBL5517669 | 0.91 | KMT2A (0.40) | LMNAALDH1A3KMT2AMAPTNPSR1 | |
| Ethylene SCHEMBL6226363 | 0.87 | LMNA (0.48) | LMNAALDH1A3MAPTTYRALDH1A1 | |
| Cyclopropane SCHEMBL6228970 | 0.85 | LMNA (0.46) | LMNAALDH1A3MAPTTYRALDH1A1 | |
| SCHEMBL10736418 | 0.84 | CYP2A6 (0.59) | LMNAALDH1A3MAPTNPSR1TYR | |
| SCHEMBL10633434 | 0.82 | TYR (0.47) | LMNAALDH1A3MAPTMAPK1TYR | |
| 4-Hydroxybenzaldehyde SCHEMBL17941268 | 0.82 | ALDH5A1 (0.57) | LMNAALDH1A3TYRALDH1A1ALDH3A1 | |
| SCHEMBL10763720 | 0.82 | HSD17B10 (0.57) | LMNAALDH1A3MAPTTYRALDH1A1 | |
| SCHEMBL7563021 | 0.82 | LMNA (0.43) | LMNAALDH1A3KMT2AMAPTNPSR1 | |
| Benzaldehyde SCHEMBL367504 | 0.81 | ALDH1A1 (0.54) | LMNAALDH1A3KMT2AMEN1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6234690-A | — | — | None | — | — | JP | disclosed |
| CN-107721811-B | Side-fluorine-containing biphenyl diluent for high-birefringence liquid crystal and synthetic method thereof | 陕西师范大学 | 2021-01-29 | — | — | CN | disclosed |
| CN-109251189-B | 3-piperazinyl chalcone derivatives, pharmaceutical compositions thereof and application thereof | 华东理工大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-109251189-A | 3 piperazinyl chalcone derivatives, its pharmaceutical composition and its application | 华东理工大学 | 2019-01-22 | — | — | CN | disclosed |
| EP-2601190-B1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC (US) | 2018-07-04 | — | — | EP | disclosed |
| US-9061013-B2 | Isoxazoline derivatives as antiparasitic agents | ZOETIS LLC (US) | 2015-06-23 | — | — | US | disclosed |
| EP-2688876-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2014-01-29 | — | — | EP | disclosed |
| US-20140011758-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC | 2014-01-09 | — | — | US | disclosed |
| EP-2601190-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | AH USA 42 LLC (US) | 2013-06-12 | — | — | EP | disclosed |
| US-8415310-B2 | Isoxazoline derivatives as antiparasitic agents | AH USA 42 LLC (US) | 2013-04-09 | — | — | US | disclosed |
| US-6080773-A | USEFUL FOR TREATMENT OF DEPRESSION, ANXIETY OR PSYCHOSIS | AKZO NOBEL, N.V. (NL) | 2000-06-27 | — | — | US | disclosed |
| EP-0898566-A1 | SUBSTITUTED BENZYLAMINES AND THEIR USE FOR THE TREATMENT OF DEPRESSION | Akzo Nobel N.V. (NL) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040027-A1 | SUBSTITUTED BENZYLAMINES AND THEIR USE FOR THE TREATMENT OF DEPRESSION | AKZO NOBEL N.V. (NL) | 1997-10-30 | — | — | WO | disclosed |
| EP-0802968-A1 | STABILIZATION OF LIQUID ENZYME COMPOSITIONS | NOVO NORDISK A/S (DK) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021716-A1 | STABILIZATION OF LIQUID ENZYME COMPOSITIONS | NOVO NORDISK A/S (DK) | 1996-07-18 | — | — | WO | disclosed |
| JP-H06234690-A | PREPARATION OF BIPHENYL DERIVATIVE | HOECHST AG | 1994-08-23 | — | — | JP | disclosed |
| EP-0153678-A1 | Cinnamic acid derivatives, processes for the preparation thereof and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-09-04 | — | — | EP | disclosed |
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011758-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | CYP3A7, CYP2W1, CYP2A7 | LMNA 2159/4885ALDH1A3 721/4885KMT2A 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.