Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517737 | 0.91 | CYP19A1 (0.44) | MAOAELANEMAOBBCHECES1 | |
| SCHEMBL27640285 | 0.84 | MAOA (0.46) | MAOAELANEMAOBBCHECES1 | |
| SCHEMBL27640476 | 0.84 | MAOA (0.52) | MAOAELANEMAOBBCHECES1 | |
| SCHEMBL2127216 | 0.77 | ELANE (0.69) | MAOAELANEMAOBCTSGALDH1A1 | |
| SCHEMBL28826604 | 0.74 | MAOA (0.47) | MAOAELANEBCHECES1MIF | |
| SCHEMBL8917078 | 0.73 | DRD2 (0.46) | MAOAELANECTSGALDH1A1APAF1 | |
| Hydrochloric Acid SCHEMBL9719382 | 0.73 | TNF (0.48) | MAOAELANEBCHECES1MIF | |
| SCHEMBL27640284 | 0.73 | MAOA (0.46) | MAOAELANEMAOBBCHECES1 | |
| SCHEMBL22720620 | 0.73 | PNMT (0.46) | ELANECTSGALDH1A1APAF1MAPT | |
| SCHEMBL13935793 | 0.72 | ELANE (0.67) | MAOAELANEMAOBBCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100509740-C | 10,10-dibenzyl anthrone and derivative and synthetic method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-100509740-C | 10,10-dibenzyl anthrone and derivative and synthetic method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-08 | — | — | CN | disclosed |
| CN-1858033-A | 10,10-dibenzyl anthrone and its derivative and synthetic method | GUANGZHOU INST CHEMISTRY CAS (CN) | 2006-11-08 | — | — | CN | disclosed |