SCHEMBL27640329

SCHEMBL27640329

CCCC(=O)ONCc1ccc([N+](=O)[O-])c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
LMNA P02545 3/20 0.43
POLB P06746 2/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 3/20 0.40
BCL9 O00512 1/20 0.40
CTNNB1 P35222 1/20 0.40
ALDH1A1 P00352 5/20 0.38
KMT2A Q03164 4/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 3/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27640326 0.76 LMNA (0.49) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL27818214 0.75 BCL9 (0.62) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL5465423 0.74 PDGFRB (0.53) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL27972753 0.74 CYP4F2 (0.54) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL26264596 0.73 LMNA (0.50) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL1828406 0.72 MAPT (0.47) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL13267383 0.72 MAPT (0.47) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL6271900 0.72 TSHR (0.51) L3MBTL1POLBTSHRRAB9ASMN1; SMN2
SCHEMBL27593722 0.72 MAPT (0.51) L3MBTL1LMNAPOLBTSHRRAB9A
SCHEMBL27621394 0.72 MEN1 (0.49) L3MBTL1LMNAPOLBTSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100522952-C Insecticidal phthalamide derivatives BAYER CROPSCIENCE AG (DE) 2009-08-05 CN disclosed
CN-1759105-A Phthalamide derivatives having insecticidal activity BAYER CROPSCIENCE AG (DE) 2006-04-12 CN disclosed