SCHEMBL27640326

SCHEMBL27640326

CCOC(=O)CNCc1ccc([N+](=O)[O-])c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.49
MAPT P10636 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
GAA P10253 2/20 0.44
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TSHR P16473 1/20 0.43
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.41
HTT P42858 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PPIB P23284 1/20 0.40
PPIA P62937 1/20 0.40
PPID Q08752 1/20 0.40
PPIG Q13427 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6271900 0.84 TSHR (0.51) MAPTSMN1; SMN2GAAALDH1A1MEN1
SCHEMBL26264596 0.82 LMNA (0.50) LMNAMAPTSMN1; SMN2GAAMAPK1
SCHEMBL4049519 0.81 LMNA (0.55) LMNAMAPTGAAALDH1A1MEN1
SCHEMBL27972753 0.80 CYP4F2 (0.54) LMNAMAPTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL8172847 0.80 RAB9A (0.53) LMNAMAPTGAAMAPK1ALDH1A1
SCHEMBL27593722 0.78 MAPT (0.51) LMNAMAPTSMN1; SMN2GAAMAPK1
SCHEMBL2321712 0.78 MEN1 (0.48) LMNAMAPTSMN1; SMN2GAAALDH1A1
SCHEMBL10677552 0.78 LMNA (0.47) LMNAMAPTSMN1; SMN2GAAMAPK1
SCHEMBL18322621 0.76 MAPK1 (0.53) LMNAMAPTSMN1; SMN2GAAMAPK1
SCHEMBL27640329 0.76 L3MBTL1 (0.43) LMNAMAPTSMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100522952-C Insecticidal phthalamide derivatives BAYER CROPSCIENCE AG (DE) 2009-08-05 CN disclosed
CN-1759105-A Phthalamide derivatives having insecticidal activity BAYER CROPSCIENCE AG (DE) 2006-04-12 CN disclosed