Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25164661 | 0.82 | PPARD (0.37) | PPARDPPARA | |
| SCHEMBL15211249 | 0.80 | PPARD (0.39) | PPARDPPARA | |
| SCHEMBL25025569 | 0.77 | SRC (0.39) | PPARDPPARAMAPT | |
| SCHEMBL4471873 | 0.73 | MAPT (0.45) | PPARDPPARAMAPT | |
| SCHEMBL28996471 | 0.72 | — | — | |
| SCHEMBL24137968 | 0.72 | PPARD (0.34) | PPARDPPARA | |
| SCHEMBL1846903 | 0.72 | — | — | |
| SCHEMBL13841474 | 0.72 | NOS1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL4858282 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL977726 | 0.70 | MAPT (0.59) | PPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972916-B | Cinnamide compounds | EISAI R&D MAN CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-101723900-B | Cinnamide compounds | EISAI R&D MAN CO LTD | 2012-08-22 | — | — | CN | disclosed |
| CN-101830863-B | Method and intermediate compound for preparing ligand of PPAR (Peroxisome Proliferator-Activated Receptor) delta | SEOUL NAT UNIV IND FOUNDATION | 2011-06-22 | — | — | CN | disclosed |
| CN-101193876-B | Process for preparing ligands for PPAR δ and intermediate compounds useful for preparing the ligands | SEOUL NAT UNIV IND FOUNDATION | 2011-05-11 | — | — | CN | disclosed |
| CN-101830863-A | The method and the intermediate compound that is used to prepare this part of the part of preparation PPAR δ | SEOUL NAT UNIV IND FOUNDATION | 2010-09-15 | — | — | CN | disclosed |
| CN-101723900-A | Cinnamide compounds | EISAI R&D MAN CO LTD | 2010-06-09 | — | — | CN | disclosed |
| CN-100457744-C | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NAT UNIV IND FOUNDATION (KR) | 2009-02-04 | — | — | CN | disclosed |
| CN-101193876-A | Process for preparing ligands for PPAR δ and intermediate compounds useful for preparing the ligands | JIANG XIANZHONG (KR) | 2008-06-04 | — | — | CN | disclosed |
| CN-1972916-A | Cinnamide compounds | EISAI R&D MAN CO LTD (JP) | 2007-05-30 | — | — | CN | disclosed |
| CN-1750820-A | Thiazole and oxazole derivatives which modulate PPAR activity | WARNER LAMBERT CO (US) | 2006-03-22 | — | — | CN | disclosed |
| CN-1649854-A | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | HEONJOONG KANG (KR) | 2005-08-03 | — | — | CN | disclosed |