Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 10/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788547 | 0.89 | MPO (0.52) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL3741787 | 0.82 | KMT2A (0.56) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL4602724 | 0.82 | KMT2A (0.47) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL13957453 | 0.80 | CAPN1 (0.56) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL4602807 | 0.79 | MEN1 (0.45) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL27640739 | 0.79 | GPR84 (0.54) | GPR84HTR2AHTR2CTRPM8 | |
| SCHEMBL29935857 | 0.79 | CAPN1 (0.59) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL208051 | 0.79 | CAPN1 (0.59) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL28600077 | 0.76 | CAPN1 (0.52) | MPOGPR84MEN1NPC1USP2 | |
| SCHEMBL21665304 | 0.76 | CAPN1 (0.59) | MPOGPR84MEN1NPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1860112-A | 3-amino chroman and 2-amino tetralin derivatives | WYETH CORP (US) | 2006-11-08 | — | — | CN | claimed |
| CN-1860112-A | 3-amino chroman and 2-amino tetralin derivatives | WYETH CORP (US) | 2006-11-08 | — | — | CN | disclosed |